Cleaved-Caspase 6 p18 Rabbit Polyclonal Antibody

Cleaved-Caspase 6 p18 Rabbit Polyclonal Antibody

规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):WB,IHC-P,ELISA

种属(Reactivity):Human,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CASP6
SKU: APRab00828 Category: 兔多克隆抗体 Tags: , , , , , , ,

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产品概述

产品名称(Product Name)

Cleaved-Caspase 6 p18 Rabbit Polyclonal Antibody

描述(Description)

Rabbit polyclonal Antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ELISA

种属反应性(Reactivity)

Human,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Polyclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Liquid in PBS containing 50% glycerol, 0.5% protective protein and 0.02% sodium azide, pH 7.3.

纯化方式(Purification)

Affinity Chromatography

 

免疫原

基因名(Gene Name)

CASP6

别名(Alternative Names)

CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2

基因ID(Gene ID)

839

蛋白ID(SwissProt ID)

P55212

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IHC 1:50-1:100,ELISA 1:5000-1:20000

蛋白分子量(Molecular Weight)

Calculated MW: 33 kDa; Observed MW: 20,35 kDa

 

研究背景

Caspase-6 (Mch2) is one of the major executioner caspases functioning in cellular apoptotic processes. Upon apoptotic stimulation, initiator caspases such as caspase-9 are cleaved and activated. The activated upstream caspases further process downstream executioner caspases, such as caspase-3 and caspase-6, by cleaving them into large and small subunits, thereby initiating a caspase cascade leading to apoptosis. One of the major targets for caspase-6 is the membrane associated protein lamin A.

 

研究领域

Cell Biology


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