English

Aconitase 1 (7U6) Rabbit Monoclonal Antibody【50ul/100ul买二送一】

Aconitase 1 (7U6) Rabbit Monoclonal Antibody【50ul/100ul买二送一】

Cat: AMRe06511
★ ★ ★ ★ ★
规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB,ICC/IF,FC
种属（Reactivity）：Human,Mouse,Rat
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：ACO1
分类: 兔单克隆抗体 标签: , , , , , , , ,

说明书 复制

产品概述

产品名称（Product Name）

Aconitase 1 (7U6) Rabbit Monoclonal Antibody

描述（Description）

Recombinant rabbit monoclonal antibody

宿主（Host）

Rabbit

应用（Application）

WB,ICC/IF,FC

种属反应性（Reactivity）

Human,Mouse,Rat

 

产品性能

偶联物（Conjugation）

Unconjugated

修饰（Modification）

Unmodified

同种型（Isotype）

IgG

克隆（Clonality）

Monoclonal

形式（Form）

Liquid

存放说明（Storage）

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液（Buffer）

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式（Purification）

Affinity purification

 

免疫原

基因名（Gene Name）

ACO1

别名（Alternative Names）

ACO 1; Aconitase; Citrate hydro lyase; IREB1; IRP 1; Iron responsive element binding protein 1;

基因ID（Gene ID）

48

蛋白ID（SwissProt ID）

P21399

 

产品应用

稀释比（Dilution Ratio）

WB 1:500-1:2000,ICC/IF 1:100-1:200,FC 1:50-1:200

蛋白分子量（Molecular Weight）

98kDa

 

研究背景

Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Bifunctional iron sensor that switches between 2 activities depending on iron availability (PubMed:1946430, PubMed:1281544, PubMed:8041788). Iron deprivation, promotes its mRNA binding activity through which it regulates the expression of genes involved in iron uptake, sequestration and utilization (PubMed:1946430, PubMed:1281544, PubMed:8041788, PubMed:23891004). Binds to iron-responsive elements (IRES) in the untranslated region of target mRNAs preventing for instance the translation of ferritin and aminolevulinic acid synthase and stabilizing the transferrin receptor mRNA (PubMed:1946430, PubMed:1281544, PubMed:8041788, PubMed:23891004).

 

研究领域

Cardiovascular; Blood; Signal Transduction; Metabolism; Energy Metabolism; Epigenetics and Nuclear Signaling; DNA / RNA; RNA Processing; Vitamins / Minerals; Pathways and Processes; Metabolic signaling pathways; Nucleotide metabolism; Energy transfer pathways; Energy Metabolism;

相关产品


  • 027-87002838

  • order@enkilife.cn

  • 微信客服
  • 企业微信
    • 在线留言
    关闭
    function uet_report_conversion() { window.uetq = window.uetq || []; window.uetq.push('event', 'wechat_qr_click', { "event_label": "wechat_qr", "event_category": "lead" }); } (function() { var fired = false; function fireWechatConversion() { if (fired) return; fired = true; uet_report_conversion(); } document.addEventListener('click', function(e) { if ( e.target.closest('.rightNav li.howshow') && e.target.closest('.rightNav li.howshow').querySelector('.fa-wechat, .fa-qrcode') ) { fireWechatConversion(); } }); document.addEventListener('mouseover', function(e) { var item = e.target.closest('.rightNav li.howshow'); if (!item) return; if (!item.querySelector('.fa-wechat, .fa-qrcode')) return; var from = e.relatedTarget; if (from && item.contains(from)) return; fireWechatConversion(); }); })();