CCR7 Rabbit Monoclonal Antibody

CCR7 Rabbit Monoclonal Antibody

Cat: AMRe87677
★ ★ ★ ★ ★
规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,ICC/IF,IP

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CCR7

分类: 兔单克隆抗体 标签: , , , , , , , ,

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产品概述

产品名称(Product Name)

CCR7 Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ICC/IF,IP

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

CCR7

别名(Alternative Names)

BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7

基因ID(Gene ID)

1236

蛋白ID(SwissProt ID)

P32248

 

产品应用

稀释比(Dilution Ratio)

WB 1:2000-1:10000,IHC 1:50-1:200,ICC/IF 1:100-1:200,IP 1:20-1:50

蛋白分子量(Molecular Weight)

Calculated MW:43 kDa; Observed MW:43 kDa

 

研究背景

The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]

 

研究领域


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