NFkB p105/p50 Rabbit Monoclonal Antibody-EnkiLife

NFkB p105/p50 Rabbit Monoclonal Antibody

规格：20μL 价格：￥680
规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB, IHC-P
种属（Reactivity）：Human,Mouse,Rat
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：NFkB p105/p50 SKU: AMRe87472 Category: 兔单克隆抗体 Tags: Rabbit, Unconjugated, WB, IHC-P, Human, Mouse, Rat

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产品概述

产品名称（Product Name）	NFkB p105/p50 Rabbit Monoclonal Antibody
描述（Description）	Rabbit Monoclonal antibody
宿主（Host）	Rabbit
应用（Application）	WB, IHC-P
种属反应性（Reactivity）	Human,Mouse,Rat

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	IgG
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
纯化方式（Purification）	Affinity Purification

免疫原

基因名（Gene Name）	NFkB p105/p50
别名（Alternative Names）	p50; KBF1; p105; EBP-1; CVID12; NF-kB1; NFKB-p50; NFkappaB; NF-kappaB; NFKB-p105; NF-kappa-B
基因ID（Gene ID）	4790, 18033, 81736
蛋白ID（SwissProt ID）	P19838, P25799, Q63369

产品应用

稀释比（Dilution Ratio）	WB: 1:1000-1:5000 IHC-P: 1:200-1:500
蛋白分子量（Molecular Weight）	Calculated MW:105 kDa; Observed MW:105,50 kDa

研究背景

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isoforms, at least one of which is proteolytically processed. [provided by RefSeq, Feb 2016]