Integrin alpha 6 Rabbit Monoclonal Antibody-EnkiLife

Integrin alpha 6 Rabbit Monoclonal Antibody

规格：20μL 价格：￥680
规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB, IHC-P
种属（Reactivity）：Human,Mouse,Rat
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：Integrin alpha 6 SKU: AMRe86732 Category: 兔单克隆抗体 Tags: Rabbit, Unconjugated, WB, IHC-P, Human, Mouse, Rat

说明书复制

产品概述

产品名称（Product Name）	Integrin alpha 6 Rabbit Monoclonal Antibody
描述（Description）	Rabbit Monoclonal antibody
宿主（Host）	Rabbit
应用（Application）	WB, IHC-P
种属反应性（Reactivity）	Human,Mouse,Rat

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	IgG
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
纯化方式（Purification）	Affinity Purification

免疫原

基因名（Gene Name）	Integrin alpha 6
别名（Alternative Names）	CD49f; VLA-6; ITGA6B
基因ID（Gene ID）	3655
蛋白ID（SwissProt ID）	P23229

产品应用

稀释比（Dilution Ratio）	WB: 1:1000 IHC-P: 1:200-1:500
蛋白分子量（Molecular Weight）	Calculated MW:127 kDa; Observed MW:127 kDa

研究背景

The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]