EAAT2 Rabbit Monoclonal Antibody

EAAT2 Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB, IHC-P, IP

种属(Reactivity):Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):EAAT2
SKU: AMRe86630 Category: 兔单克隆抗体 Tags: , , , , , ,

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产品概述

产品名称(Product Name)

EAAT2 Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB, IHC-P, IP

种属反应性(Reactivity)

Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

EAAT2

别名(Alternative Names)

GLT1; Eaat2; GLT-1; MGLT1; AI159670; 1700091C19Rik; 2900019G14Rik

基因ID(Gene ID)

20511

蛋白ID(SwissProt ID)

P43006

 

产品应用

稀释比(Dilution Ratio)

WB: 1:1000 IHC-P: 1:200-1:1000 IP: 1:20-1:50

蛋白分子量(Molecular Weight)

Calculated MW:62 kDa; Observed MW:65 kDa

 

研究背景

Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:7698742, PubMed:7557442, PubMed:9373176). Functions as a symporter that transports one amino acid molecule together with two or three Na+ ions and one proton, in parallel with the counter-transport of one K+ ion. Mediates Cl- flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na+ symport (By similarity). Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate (PubMed:9180080).

 


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