XRCC4 Mouse Monoclonal Antibody

XRCC4 Mouse Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IP,IHC,ICC

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):XRCC4
SKU: AMM85018 Category: 鼠单克隆抗体 Tags: , , , , , , , ,

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产品概述

产品名称(Product Name)

XRCC4 Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB,IHC,ICC,IP

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

Mouse IgG1

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in PBS with 0.05% sodium azide,0.5%protective protein and 50% glycerol.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

XRCC4

别名(Alternative Names)

X ray repair cross complementing protein 4; DNA repair protein XRCC4; DNA double strand break repair

基因ID(Gene ID)

7518

蛋白ID(SwissProt ID)

Q13426

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IHC 1:50-1:100,ICC 1:50-1:200,IP 1:10-1:20

蛋白分子量(Molecular Weight)

Calculated MW: 38 kDa; Observed MW: 38-45 kDa

 

研究背景

Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

 

研究领域


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