Proteinase 3 Mouse Monoclonal Antibody

Proteinase 3 Mouse Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):ICC,FC,ELISA

种属(Reactivity):Human,Mouse
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Proteinase 3
SKU: AMM80762 Category: 鼠单克隆抗体 Tags: , , , , , ,

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产品概述

产品名称(Product Name)

Proteinase 3 Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

ICC,ELISA,FC

种属反应性(Reactivity)

Human,Mouse

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

Mouse IgG2b

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in PBS with 0.05% sodium azide.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Proteinase 3

别名(Alternative Names)

PRTN3; ACPA; CANCA

基因ID(Gene ID)

5657

蛋白ID(SwissProt ID)

P24158

 

产品应用

稀释比(Dilution Ratio)

ICC 1:50-1:200,ELISA 1:5000-1:20000,FC 1:200-1:400

蛋白分子量(Molecular Weight)

28kDa

 

研究背景

Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes. Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegener's granulomatosis.

 

研究领域


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