IL-2 Mouse Monoclonal Antibody

IL-2 Mouse Monoclonal Antibody

Cat: AMM80713
★ ★ ★ ★ ★
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,ICC,ELISA

种属(Reactivity):Human,Mouse,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):IL-2

分类: 鼠单克隆抗体 标签: , , , , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

IL-2 Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB,ICC,ELISA

种属反应性(Reactivity)

Human,Mouse,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

Mouse IgG1

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in PBS with 0.05% sodium azide.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

IL-2

别名(Alternative Names)

Aldesleukin; TCGF; interleukin-2

基因ID(Gene ID)

3558

蛋白ID(SwissProt ID)

P60568

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,ICC 1:200-1:1000,ELISA 1:5000-1:20000

蛋白分子量(Molecular Weight)

17.6kDa

 

研究背景

IL-2: interleukin-2. Entrez Protein NP_000577. It is a 17.6kDa secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

 

研究领域

TGF-beta signaling pathway,PI3K-Akt signaling pathway


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