AF10 Rabbit Monoclonal Antibody

AF10 Rabbit Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):MLLT10
SKU: AMRe01619 Category: 兔单克隆抗体 Tags: , , , , ,

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产品概述

产品名称(Product Name)

AF10 Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC-P

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal Antibody

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

MLLT10

别名(Alternative Names)

MLLT10; AF10; Protein AF-10; ALL1-fused gene from chromosome 10 protein

基因ID(Gene ID)

8028

蛋白ID(SwissProt ID)

P55197

 

产品应用

稀释比(Dilution Ratio)

WB: 1:500-1:1000 IHC: 1:50-1:100

蛋白分子量(Molecular Weight)

Calculated MW: 113 kDa; Observed MW: 140 kDa

 

研究背景

Probably involved in transcriptional regulation. In vitro or as fusion protein with KMT2A/MLL1 has transactivation activity. Binds to cruciform DNA. In cells, binding to unmodified histone H3 regulates DOT1L functions including histone H3 'Lys-79' dimethylation (H3K79me2) and gene activation (PubMed:26439302).

 

研究领域

Epigenetics and Nuclear Signaling


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