HOPX Rabbit Monoclonal Antibody

HOPX Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IP

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):HOPX
SKU: AMRe85669 Category: 兔单克隆抗体 Tags: , , , ,

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产品概述

产品名称(Product Name)

HOPX Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IP

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

HOPX

别名(Alternative Names)

Hod; Hop; Ob1; Obl; Hdop; Toto; Cameo; AI848177; AW490897; 1110018K11Rik; 1200015P04Rik; 2300002F06Rik

基因ID(Gene ID)

74318

蛋白ID(SwissProt ID)

Q8R1H0

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IP 1:10-1:20

蛋白分子量(Molecular Weight)

Calculated MW: 8 kDa; Observed MW: 12 kDa

 

研究背景

Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (PubMed:12297045, PubMed:12297046). Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding .

 

研究领域


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