Lin28B Rabbit Monoclonal Antibody

Lin28B Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,ICC/IF,FC,IP

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Lin28B
SKU: AMRe87762 Category: 兔单克隆抗体 Tags: , , , , , ,

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产品概述

产品名称(Product Name)

Lin28B Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,ICC/IF,FC,IP

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Lin28B

别名(Alternative Names)

CSDD2

基因ID(Gene ID)

389421

蛋白ID(SwissProt ID)

Q6ZN17

 

产品应用

稀释比(Dilution Ratio)

WB: 1:1000 ICC/IF: 1:200 FC: 1:20 IP: 1:20

蛋白分子量(Molecular Weight)

Calculated MW:27 kDa; Observed MW:35 kDa

 

研究背景

The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012]

 


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