Phospho-TIFA (Thr9) Rabbit Monoclonal Antibody

Phospho-TIFA (Thr9) Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB, IP

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Phospho-TIFA
SKU: AMRe87618 Category: 兔单克隆抗体 Tags: , , , ,

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产品概述

产品名称(Product Name)

Phospho-TIFA (Thr9) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IP

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Phosphorylated

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Phospho-TIFA

别名(Alternative Names)

T2BP; T6BP; TIFAA

基因ID(Gene ID)

92610

蛋白ID(SwissProt ID)

Q96CG3

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:2000,IP 1:20-1:50

蛋白分子量(Molecular Weight)

Calculated MW:21 kDa; Observed MW:21 kDa

 

研究背景

This gene encodes an adapter protein involved in adaptive and innate immunity. This protein includes a forkhead-associated (FHA) domain that specifically binds to phosphorylated serine and threonine residues. In response to bacterial infection, the encoded host cell protein undergoes an intermolecular interaction between the FHA domain and a phosphorylated threonine that leads to protein oligomerization and stimulation of the NF-kappa B and other downstream signaling pathways. This protein exhibits reduced expression in hepatocellular carcinoma and may suppress hepatocellular carcinoma progression. This protein may also play a role in the DNA damage response. [provided by RefSeq, Jun 2018]

 

研究领域


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