Ku80 Rabbit Monoclonal Antibody

Ku80 Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB, IHC-P, FC

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Ku80
SKU: AMRe87254 Category: 兔单克隆抗体 Tags: , , , , ,

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产品概述

产品名称(Product Name)

Ku80 Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB, IHC-P, FC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Ku80

别名(Alternative Names)

KU80; KUB2; Ku86; NFIV; KARP1; KARP-1

基因ID(Gene ID)

7520

蛋白ID(SwissProt ID)

P13010

 

产品应用

稀释比(Dilution Ratio)

WB: 1:1000 IHC-P: 1:200-1:500 FC: 1:100

蛋白分子量(Molecular Weight)

Calculated MW:83 kDa; Observed MW:83 kDa

 

研究背景

The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq, Jul 2008]

 


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