Lin28A Rabbit Monoclonal Antibody

Lin28A Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB, ICC/IF, FC, IP

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Lin28A
SKU: AMRe86310 Category: 兔单克隆抗体 Tags: , , , , , ,

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产品概述

产品名称(Product Name)

Lin28A Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB, ICC/IF, FC, IP

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Lin28A

别名(Alternative Names)

CSDD1; LIN28; LIN-28; ZCCHC1; lin-28A

基因ID(Gene ID)

79727

蛋白ID(SwissProt ID)

Q9H9Z2

 

产品应用

稀释比(Dilution Ratio)

WB: 1:2000-1:20000 ICC/IF: 1:100-1:500 FC: 1:10-1:100 IP: 1:10-1:100

蛋白分子量(Molecular Weight)

Calculated MW:23 kDa; Observed MW:26 kDa

 

研究背景

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]

 


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