RAD18 Mouse Monoclonal Antibody

RAD18 Mouse Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):FC,ELISA

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):RAD18
SKU: AMM81541 Category: 鼠单克隆抗体 Tags: , , , ,

说明书 复制

产品概述

产品名称(Product Name)

RAD18 Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

ELISA,FC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

Mouse IgG1

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in PBS with 0.05% sodium azide

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

RAD18

别名(Alternative Names)

RNF73

基因ID(Gene ID)

56852

蛋白ID(SwissProt ID)

Q9NS91

 

产品应用

稀释比(Dilution Ratio)

ELISA 1:5000-1:20000,FC 1:200-1:400

蛋白分子量(Molecular Weight)

56.2kDa

 

研究背景

The protein encoded by this gene is highly similar to S. cerevisiae DNA damage repair protein Rad18. Yeast Rad18 functions through its interaction with Rad6, which is an ubiquitin-conjugating enzyme required for post-replication repair of damaged DNA. Similar to its yeast counterpart, this protein is able to interact with the human homolog of yeast Rad6 protein through a conserved ring-finger motif. Mutation of this motif results in defective replication of UV-damaged DNA and hypersensitivity to multiple mutagens.

 

研究领域


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