Mast Cell Tryptase (7Q2) Rabbit Monoclonal Antibody

Mast Cell Tryptase (7Q2) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):IHC-P,IF-P

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):TPSAB1
SKU: AMRe13658 Category: 兔单克隆抗体 Tags: , , , , ,

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产品概述

产品名称(Product Name)

Mast Cell Tryptase (7Q2) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

IHC,IF-P

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

TPSAB1

别名(Alternative Names)

TPS1; TPS2; TPSAB1; TPSB1; MCP 7 ; Mast cell protease 7; Tryptase alpha 1;

基因ID(Gene ID)

7177

蛋白ID(SwissProt ID)

Q15661

 

产品应用

稀释比(Dilution Ratio)

IHC 1:200-1:1000,IF-P 1:200-1:1000

蛋白分子量(Molecular Weight)

31kDa

 

研究背景

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. Isoform 2 cleaves large substrates, such as fibronectin, more efficiently than isoform 1, but seems less efficient toward small substrates (PubMed:18854315).

 

研究领域


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