pro Caspase 7 (10O2) Rabbit Monoclonal Antibody-EnkiLife

pro Caspase 7 (10O2) Rabbit Monoclonal Antibody

规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB,IHC-P,IHC-F,ICC/IF,IF-P,IF-F
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：CASP7 SKU: AMRe16509 Category: 兔单克隆抗体 Tags: Human, WB, IHC-P, IHC-F, ICC/IF, IF-P, IF-F, Unconjugated, Rabbit, -

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产品概述

产品名称（Product Name）	pro Caspase 7 (10O2) Rabbit Monoclonal Antibody
描述（Description）	Recombinant rabbit monoclonal antibody
宿主（Host）	Rabbit
应用（Application）	WB,IHC,ICC/IF
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	IgG
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
纯化方式（Purification）	Affinity purification

免疫原

基因名（Gene Name）	CASP7
别名（Alternative Names）	apoptosis-related cysteine peptidase; Apoptotic protease Mch-3; CASP-7; Caspase-7 subunit p11; CMH-1; ICE-LAP3; ICE-like apoptotic protease 3;
基因ID（Gene ID）	840
蛋白ID（SwissProt ID）	P55210

产品应用

稀释比（Dilution Ratio）	WB 1:1000-1:2000,IHC 1:100-1:200,ICC/IF 1:50-1:200
蛋白分子量（Molecular Weight）	34kDa

研究背景

Belongs to the peptidase C14A family. Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp--Gly-217' bond. Overexpression promotes programmed cell death. Involved in the activation cascade of caspases responsible for apoptosis execution (PubMed:8521391, PubMed:8576161, PubMed:8567622, PubMed:9070923, PubMed:11701129). Cleaves and activates sterol regulatory element binding proteins (SREBPs) (PubMed:8521391, PubMed:8576161, PubMed:8567622, PubMed:9070923). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death (PubMed:8521391, PubMed:8576161, PubMed:8567622, PubMed:9070923). Cleaves phospholipid scramblase proteins XKR4, XKR8 and XKR9 (By similarity).

研究领域

Cell Biology

pro Caspase 7 (10O2) Rabbit Monoclonal Antibody

pro Caspase 7 (10O2) Rabbit Monoclonal Antibody

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