Placental Protein 14 / PAEP (11B8) Rabbit Monoclonal Antibody-EnkiLife

Placental Protein 14 / PAEP (11B8) Rabbit Monoclonal Antibody

规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：PAEP SKU: AMRe16236 Category: 兔单克隆抗体 Tags: Human, WB, Unconjugated, Rabbit, -

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产品概述

产品名称（Product Name）	Placental Protein 14 / PAEP (11B8) Rabbit Monoclonal Antibody
描述（Description）	Recombinant rabbit monoclonal antibody
宿主（Host）	Rabbit
应用（Application）	WB
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	IgG
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
纯化方式（Purification）	Affinity purification

免疫原

基因名（Gene Name）	PAEP
别名（Alternative Names）	GdA; GdF; GdS; Glycodelin A; Glycodelin; Glycodelin F; Glycodelin S; PAEG; PAEP; PEG; PEP; Placental protein 14; PP14;
基因ID（Gene ID）	5047
蛋白ID（SwissProt ID）	P09466

产品应用

稀释比（Dilution Ratio）	WB 1:1000-1:5000
蛋白分子量（Molecular Weight）	21kDa

研究背景

This protein is, quantitatively, the main protein synthesized and secreted in the endometrium from mid-luteal phase of the menstrual cycle and during the first semester of pregnancy. Glycoprotein that regulates critical steps during fertilization and also has immunomonomodulatory effects. Four glycoforms, namely glycodelin-S, -A, -F and -C have been identified in reproductive tissues that differ in glycosylation and biological activity. Glycodelin-A has contraceptive and immunosuppressive activities (PubMed:9918684, PubMed:7531163). Glycodelin-C stimulates binding of spermatozoa to the zona pellucida (PubMed:17192260). Glycodelin-F inhibits spermatozoa-zona pellucida binding and significantly suppresses progesterone-induced acrosome reaction of spermatozoa (PubMed:12672671). Glycodelin-S in seminal plasma maintains the uncapacitated state of human spermatozoa (PubMed:15883155).

研究领域