Phospho-IRE1 (Ser724) Rabbit Monoclonal Antibody

Phospho-IRE1 (Ser724) Rabbit Monoclonal Antibody

Cat: AMRe02857
★ ★ ★ ★ ★
规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IP

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):ERN1

分类: 兔单克隆抗体 标签: , , , , ,

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产品概述

产品名称(Product Name)

Phospho-IRE1 (Ser724) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IP

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Phosphorylated

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

ERN1

别名(Alternative Names)

ERN1; IRE1; Serine/threonine-protein kinase/endoribonuclease IRE1; Endoplasmic reticulum-to-nucleus signaling 1; Inositol-requiring protein 1; hIRE1p; Ire1-alpha; IRE1a

基因ID(Gene ID)

2081

蛋白ID(SwissProt ID)

O75460

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IP 1:20-1:50

蛋白分子量(Molecular Weight)

Calculated MW: 110 kDa; Observed MW: 110 kDa

 

研究背景

Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.

 

研究领域

Signal Transduction


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