Notch4 Rabbit Monoclonal Antibody

Notch4 Rabbit Monoclonal Antibody

规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):NOTCH4
SKU: AMRe02831 Category: 兔单克隆抗体 Tags: , , , ,

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产品概述

产品名称(Product Name)

Notch4 Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal Antibody

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

NOTCH4

别名(Alternative Names)

NOTCH4; INT3; Neurogenic locus notch homolog protein 4; Notch 4; hNotch4

基因ID(Gene ID)

4855

蛋白ID(SwissProt ID)

Q99466

 

产品应用

稀释比(Dilution Ratio)

WB: 1:500-1:1000

蛋白分子量(Molecular Weight)

Calculated MW: 210 kDa; Observed MW: 36 kDa

 

研究背景

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system (By similarity).

 

研究领域

Epigenetics and Nuclear Signaling


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