Cytokeratin 18 (8W18) Rabbit Monoclonal Antibody

Cytokeratin 18 (8W18) Rabbit Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,ICC/IF,FC,IF-P

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):KRT18
SKU: AMRe09736 Category: 兔单克隆抗体 Tags: , , , , , , , ,

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产品概述

产品名称(Product Name)

Cytokeratin 18 (8W18) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ICC/IF,FC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% protective protein.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

KRT18

别名(Alternative Names)

Keratin-18; CYK18; cytokeratin 18; Cytokeratin-18; K18; K1C18; keratin 18; KRT18; CK-18;

基因ID(Gene ID)

3875

蛋白ID(SwissProt ID)

P05783

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:2000,IHC 1:200-1:500,ICC/IF 1:100-1:500,FC 1:20-1:50

蛋白分子量(Molecular Weight)

48kDa

 

研究背景

K18 a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Keratin 18 and its filament partner keratin 8 are perhaps the most commonly found members of the intermediate filament gene family. Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection.

 

研究领域

Tags & Cell Markers


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