Caspase-9 (13Z10) Rabbit Monoclonal Antibody

Caspase-9 (13Z10) Rabbit Monoclonal Antibody

Cat: AMRe07987
★ ★ ★ ★ ★
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC,IF,ELISA

种属(Reactivity):Human,Mouse
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CASP9

分类: 兔单克隆抗体 标签: , , , , , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

Caspase-9 (13Z10) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,IF,ELISA

种属反应性(Reactivity)

Human,Mouse

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

CASP9

别名(Alternative Names)

APAF-3; Caspase9; ICE-LAP6; Apoptotic protease Mch-6; CASP-9; Caspase-9; Caspase-9 precursor; MCH6; RNCASP9;

基因ID(Gene ID)

842

蛋白ID(SwissProt ID)

P55211

 

产品应用

稀释比(Dilution Ratio)

IHC 1:500-1:1000;WB 1:1000-1:5000;IF 1:200-1:1000;ELISA 1:5000-1:20000,

蛋白分子量(Molecular Weight)

46kDa

 

研究背景

Caspase-9 (ICE-LAP6, Mch6) is an important member of the cysteine aspartic acid protease (caspase) family. Upon apoptotic stimulation, cytochrome c released from mitochondria associates with the 47 kDa procaspase-9/Apaf 1. Apaf-1 mediated activation of caspase-9 involves instrinsic proteolytic processing resulting in cleavage at Asp315 and producing a p35 subunit. Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

 

研究领域

Cell Biology


  • 027-87002838

  • order@enkilife.cn

  • 微信客服
  • 企业微信
  • 在线留言
    关闭
    function uet_report_conversion() { window.uetq = window.uetq || []; window.uetq.push('event', 'wechat_qr_click', { "event_label": "wechat_qr", "event_category": "lead" }); } (function() { var fired = false; function fireWechatConversion() { if (fired) return; fired = true; uet_report_conversion(); } document.addEventListener('click', function(e) { if ( e.target.closest('.rightNav li.howshow') && e.target.closest('.rightNav li.howshow').querySelector('.fa-wechat, .fa-qrcode') ) { fireWechatConversion(); } }); document.addEventListener('mouseover', function(e) { var item = e.target.closest('.rightNav li.howshow'); if (!item) return; if (!item.querySelector('.fa-wechat, .fa-qrcode')) return; var from = e.relatedTarget; if (from && item.contains(from)) return; fireWechatConversion(); }); })();