Calpain 2 (3O9) Rabbit Monoclonal Antibody【50ul/100ul买二送一】

Calpain 2 (3O9) Rabbit Monoclonal Antibody【50ul/100ul买二送一】

Cat: AMRe07867
★ ★ ★ ★ ★
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,FC

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CAPN2

分类: 兔单克隆抗体 标签: , , , , ,

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产品概述

产品名称(Product Name)

Calpain 2 (3O9) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,FC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

CAPN2

别名(Alternative Names)

CALP80; Calpain M type; Calpain-2 large subunit; Calpain2; CANP2; CANPL2; CANPml; Capa2; CAPN2; M calpain; mCANP; Millimolar calpain;

基因ID(Gene ID)

824

蛋白ID(SwissProt ID)

P17655

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:2000,FC 1:50-1:100

蛋白分子量(Molecular Weight)

80kDa

 

研究背景

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity).

 

研究领域

Signal Transduction; Signaling Pathway; Calcium Signaling; Calpain; Cell Biology; Proteolysis / Ubiquitin; Proteolytic enzymes; Cysteine protease; Calpains; Cancer; Cancer Metabolism; Response to hypoxia; Metabolism; Pathways and Processes; Metabolism processes; Hypoxia


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