Calpain 2 (3O9) Rabbit Monoclonal Antibody-EnkiLife

Calpain 2 (3O9) Rabbit Monoclonal Antibody

规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB,FC
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：CAPN2 SKU: AMRe07867 Category: 兔单克隆抗体 Tags: Human, WB, FC, Unconjugated, Rabbit, -

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产品概述

产品名称（Product Name）	Calpain 2 (3O9) Rabbit Monoclonal Antibody
描述（Description）	Recombinant rabbit monoclonal antibody
宿主（Host）	Rabbit
应用（Application）	WB,FC
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	IgG
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
纯化方式（Purification）	Affinity purification

免疫原

基因名（Gene Name）	CAPN2
别名（Alternative Names）	CALP80; Calpain M type; Calpain-2 large subunit; Calpain2; CANP2; CANPL2; CANPml; Capa2; CAPN2; M calpain; mCANP; Millimolar calpain;
基因ID（Gene ID）	824
蛋白ID（SwissProt ID）	P17655

产品应用

稀释比（Dilution Ratio）	WB 1:500-1:2000,FC 1:50-1:100
蛋白分子量（Molecular Weight）	80kDa

研究背景

Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226' (PubMed:17650508). Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs (By similarity).

研究领域

Signal Transduction; Signaling Pathway; Calcium Signaling; Calpain; Cell Biology; Proteolysis / Ubiquitin; Proteolytic enzymes; Cysteine protease; Calpains; Cancer; Cancer Metabolism; Response to hypoxia; Metabolism; Pathways and Processes; Metabolism processes; Hypoxia