CD86 Rabbit Monoclonal Antibody

CD86 Rabbit Monoclonal Antibody

Cat: AMRe03894
★ ★ ★ ★ ★
规格:20μL 价格:¥600
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC-P,ICC/IF,FC,IP

种属(Reactivity):Human,Rat
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CD86

分类: 兔单克隆抗体 标签: , , , , , , , , ,

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产品概述

产品名称(Product Name)

CD86 Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,IHC,ICC/IF,FC,IP

种属反应性(Reactivity)

Human,Rat

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

纯化方式(Purification)

Affinity Chromatography

 

免疫原

基因名(Gene Name)

CD86

别名(Alternative Names)

CD86; CD28LG2; T-lymphocyte activation antigen CD86; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD antigen CD86

基因ID(Gene ID)

942

蛋白ID(SwissProt ID)

P42081

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IHC 1:50-1:100,ICC/IF 1:50-1:200,FC 1:50-1:100,IP 1:50-1:100

蛋白分子量(Molecular Weight)

Calculated MW: 38 kDa; Observed MW: 70 kDa

 

研究背景

Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.

 

研究领域

Immunology


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