产品概述
产品性能
免疫原
产品应用
研究背景
Modulates B-cell activation responses. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin- like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells (PubMed:11313396). In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity (By similarity).
研究领域
Neuroscience; Cell Type Marker; Neural Stem Cell marker; Immunology; Adaptive Immunity; B Cells; CD; Stem Cells; Hematopoietic Progenitors; Hematopoietic Stem Cells; Human Lineage Negative; Lymphoid B; Lymphocytic Lineage; T Lymphocytic Lineage; Myeloid; Dendritic Cell Lineage; Monocytic Lineage; Neutrophil Lineage; Erythrocytic Lineage; Cancer; Tumor biomarkers; Tumor antigens; Cancer Metabolism; Response to hypoxia; Cellular metabolic process; Metabolism; Pathways and Processes; Metabolism processes; Hypoxia
