CCL4/MIP1 beta (2H8) Rabbit Monoclonal Antibody【50ul/100ul买二送一】

CCL4/MIP1 beta (2H8) Rabbit Monoclonal Antibody【50ul/100ul买二送一】

Cat: AMRe08145
★ ★ ★ ★ ★
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,ICC/IF,IP

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CCL4

分类: 兔单克隆抗体 标签: , , , , , ,

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产品概述

产品名称(Product Name)

CCL4/MIP1 beta (2H8) Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB,ICC/IF,IP

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

纯化方式(Purification)

Affinity purification

 

免疫原

基因名(Gene Name)

CCL4

别名(Alternative Names)

ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1;MIP-1-beta;

基因ID(Gene ID)

388372;6351

蛋白ID(SwissProt ID)

P13236

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000-1:10000,ICC/IF 1:100-1:200,IP 1:50-1:100

蛋白分子量(Molecular Weight)

10kDa

 

研究背景

Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T- cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1- beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.

 

研究领域

Immunology; Innate Immunity; Chemokines; Beta Chemokines (CC); Macrophage / Inflamm; Immune System Diseases; Antiviral Signaling; HIV-related; Cytokines and cytokine receptors ELISA kits; Neuroscience


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