Drosha Rabbit Monoclonal Antibody

Drosha Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB, IHC-P

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Drosha
SKU: AMRe87469 Category: 兔单克隆抗体 Tags: , , , ,

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产品概述

产品名称(Product Name)

Drosha Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB, IHC-P

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Drosha

别名(Alternative Names)

RN3; ETOHI2; RNASEN; RANSE3L; RNASE3L; HSA242976

基因ID(Gene ID)

29102

蛋白ID(SwissProt ID)

Q9NRR4

 

产品应用

稀释比(Dilution Ratio)

WB: 1:2000-1:20000 IHC-P: 1:50-1:100

蛋白分子量(Molecular Weight)

Calculated MW:159 kDa; Observed MW:159 kDa

 

研究背景

This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. [provided by RefSeq, Sep 2016]

 


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