RASSF1 Rabbit Monoclonal Antibody-EnkiLife

RASSF1 Rabbit Monoclonal Antibody

规格：20μL 价格：￥680
规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB, IHC-P
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：RASSF1 SKU: AMRe87125 Category: 兔单克隆抗体 Tags: Rabbit, Unconjugated, WB, IHC-P, Human

说明书复制

产品概述

产品名称（Product Name）	RASSF1 Rabbit Monoclonal Antibody
描述（Description）	Rabbit Monoclonal antibody
宿主（Host）	Rabbit
应用（Application）	WB, IHC-P
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	IgG
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
纯化方式（Purification）	Affinity Purification

免疫原

基因名（Gene Name）	RASSF1
别名（Alternative Names）	123F2; RDA32; NORE2A; RASSF1A; REH3P21
基因ID（Gene ID）	11186
蛋白ID（SwissProt ID）	Q9NS23

产品应用

稀释比（Dilution Ratio）	WB: 1:1000-1:5000 IHC-P: 1:50-1:100
蛋白分子量（Molecular Weight）	Calculated MW:39 kDa; Observed MW:39 kDa

研究背景

This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011]