BCL-6 Rabbit Monoclonal Antibody

BCL-6 Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB, IHC-P

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):BCL-6
SKU: AMRe86645 Category: 兔单克隆抗体 Tags: , , , ,

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产品概述

产品名称(Product Name)

BCL-6 Rabbit Monoclonal Antibody

描述(Description)

Rabbit Monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB, IHC-P

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

BCL-6

别名(Alternative Names)

BCL5; LAZ3; BCL6A; ZNF51; ZBTB27

基因ID(Gene ID)

604

蛋白ID(SwissProt ID)

P41182

 

产品应用

稀释比(Dilution Ratio)

WB: 1:1000-1:5000 IHC-P: 1:200-1:2000

蛋白分子量(Molecular Weight)

Calculated MW:78 kDa; Observed MW:78 kDa

 

研究背景

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Aug 2015]

 


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