SMC1A Mouse Monoclonal Antibody-EnkiLife

SMC1A Mouse Monoclonal Antibody

规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB,ICC
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：SMC1A SKU: AMM85089 Category: 鼠单克隆抗体 Tags: Mouse, Unconjugated, WB, ICC, Human

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产品概述

产品名称（Product Name）	SMC1A Mouse Monoclonal Antibody
描述（Description）	Mouse monoclonal Antibody
宿主（Host）	Mouse
应用（Application）	WB,ICC
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	Mouse IgG1
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Purified antibody in PBS with 0.05% sodium azide,0.5%protective protein and 50% glycerol.
纯化方式（Purification）	Affinity Purification

免疫原

基因名（Gene Name）	SMC1A
别名（Alternative Names）	Chromosome segregation protein SmcB; DXS423E; KIAA0178; MGC138332; Sb1.8; Segregation of mitotic chromosomes 1; SMC protein 1A; SMC-1-alpha; SMC-1A; SMC1 (structural maintenance of chromosomes 1 yeast) like 1; SMC1; SMC1 structural maintenance of chromosomes 1 like 1; SMC1A; SMC1A_HUMAN; SMC1alpha; SMC1L1; SMCB; Structural maintenance of chromosomes 1A; Structural maintenance of chromosomes protein 1A.
基因ID（Gene ID）	8243
蛋白ID（SwissProt ID）	Q14683

产品应用

稀释比（Dilution Ratio）	WB 1:500-1:1000,ICC 1:50-1:200
蛋白分子量（Molecular Weight）	Calculated MW: 143 kDa; Observed MW: 143 kDa

研究背景

Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair . ATM/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser966 in response to ionizing radiation (IR) as part of the intra-S-phase DNA damage checkpoint. SMC1 phosphorylation is ATM-independent in cells subjected to other forms of DNA damage, including UV light and hydroxyurea treatment.

研究领域