CD45 Mouse Monoclonal Antibody

CD45 Mouse Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB,IHC,ICC

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):CD45
SKU: AMM85077 Category: 鼠单克隆抗体 Tags: , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

CD45 Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

WB,IHC,ICC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

Mouse IgG1

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in PBS with 0.05% sodium azide,0.5%protective protein and 50% glycerol.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

CD45

别名(Alternative Names)

GP180; L CA; CD45 antigen

基因ID(Gene ID)

19264

蛋白ID(SwissProt ID)

P08575

 

产品应用

稀释比(Dilution Ratio)

WB 1:500-1:1000,IHC 1:50-1:100,ICC 1:50-1:200

蛋白分子量(Molecular Weight)

Calculated MW: 145 kDa; Observed MW: 145 kDa

 

研究背景

Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN . Dephosphorylates LYN, and thereby modulates LYN activity.

 

研究领域


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