NR1H2 Mouse Monoclonal Antibody

NR1H2 Mouse Monoclonal Antibody

规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):ICC,FC,ELISA

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):NR1H2
SKU: AMM82744 Category: 鼠单克隆抗体 Tags: , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

NR1H2 Mouse Monoclonal Antibody

描述(Description)

Mouse monoclonal Antibody

宿主(Host)

Mouse

应用(Application)

ICC,ELISA,FC

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

Mouse IgG2b

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Purified antibody in PBS with 0.05% sodium azide

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

NR1H2

别名(Alternative Names)

NER; UNR; LXRB; LXR-b; NER-I; RIP15

基因ID(Gene ID)

7376

蛋白ID(SwissProt ID)

P55055

 

产品应用

稀释比(Dilution Ratio)

ICC 1:200-1:1000,ELISA 1:5000-1:20000,FC 1:200-1:400

蛋白分子量(Molecular Weight)

51kDa

 

研究背景

The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).

 

研究领域


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