产品概述
产品性能
免疫原
产品应用
研究背景
Dkk-3 (Dickkopf-3) is a member of the dickkopf family. It is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. This secreted protein is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene.
研究领域
Wnt signaling pathway
