Dynamin-1 Mouse Monoclonal Antibody-EnkiLife

Dynamin-1 Mouse Monoclonal Antibody

Cat: AMM80543

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规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB,IHC,ELISA
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：Dynamin-1
分类: 鼠单克隆抗体标签: Mouse, Unconjugated, WB, IHC, ELISA, Human

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产品概述

产品名称（Product Name）	Dynamin-1 Mouse Monoclonal Antibody
描述（Description）	Mouse monoclonal Antibody
宿主（Host）	Mouse
应用（Application）	WB,IHC,ELISA
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	Mouse IgG2a
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	PBS containing 0.03% sodium azide.
纯化方式（Purification）	Affinity Purification

免疫原

基因名（Gene Name）	Dynamin-1
别名（Alternative Names）	DNM; DNM1
基因ID（Gene ID）	1759
蛋白ID（SwissProt ID）	Q05193

产品应用

稀释比（Dilution Ratio）	WB 1:500-1:2000,IHC 1:200-1:1000,ELISA 1:5000-1:20000
蛋白分子量（Molecular Weight）	97kDa

研究背景

Dynamin-1 (Dyn1), with 864-amino acid protein (about 95kDa), belongs to the dynamin family. Dynamin-1 (neuron-specific), dynamin-2 (ubiquitously expressed), and dynamin-3 (expressed only in the testis, brain, and lung), constitute the dynamin family. Members of the dynamin family are GPTase, microtubule-associated proteins which are involved in endocytosis, synaptic transmission and neurogenesis. Dynamin-1 is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C. Dynamin-1 is a large GTPase enzyme required in membrane constriction and fission during multiple forms of endocytosis. Dynamin-1 is also a key molecule required for the recycling of synaptic vesicles in neurons, and it has been known that dynamin-1 gene expression is induced during neuronal differentiation.

研究领域