CD117(C-kit) Mouse Monoclonal Antibody

CD117(C-kit) Mouse Monoclonal Antibody

Cat: AMM22170
规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):IHC,ELISA

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):KIT SCFR

分类: 病理IHC抗体 标签: , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

CD117(C-kit) Mouse Monoclonal Antibody

描述(Description)

病理IHC抗体

宿主(Host)

Mouse

应用(Application)

IHC,ELISA

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG2b,Kappa

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化方式(Purification)

The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

 

免疫原

基因名(Gene Name)

KIT SCFR

别名(Alternative Names)

Mast/stem cell growth factor receptor Kit;SCFR;Piebald trait protein;PBT;Proto-oncogene c-Kit;Tyrosine-protein kinase Kit;p145 c-kit;v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog;CD antigen CD117;

基因ID(Gene ID)

Human:3815

蛋白ID(SwissProt ID)

Human:P10721

 

产品应用

稀释比(Dilution Ratio)

IHC 1:50-200;ELISA 1:500-5000

蛋白分子量(Molecular Weight)

Calculated MW:120kDa,Observed MW:150kDa

 

研究背景

This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

 

研究领域

Pathology


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