TCL1 Mouse Monoclonal Antibody

TCL1 Mouse Monoclonal Antibody

Cat: AMM22159
规格:50μL 价格:¥1200
规格:100μL 价格:¥2150
应用(Application):IHC,ELISA

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):TCL1A TCL1

分类: 病理IHC抗体 标签: , , , , ,

说明书 复制

产品概述

产品名称(Product Name)

TCL1 Mouse Monoclonal Antibody

描述(Description)

病理IHC抗体

宿主(Host)

Mouse

应用(Application)

IHC,ELISA

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG2b,Kappa

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

纯化方式(Purification)

The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

 

免疫原

基因名(Gene Name)

TCL1A TCL1

别名(Alternative Names)

T-cell leukemia/lymphoma protein 1A;Oncogene TCL-1;Oncogene TCL1;Protein p14 TCL1;

基因ID(Gene ID)

Human:8115

蛋白ID(SwissProt ID)

Human:P56279

 

产品应用

稀释比(Dilution Ratio)

IHC 1:200-400;ELISA 1:500-5000

蛋白分子量(Molecular Weight)

Calculated MW:13kDa,Observed MW:13kDa

 

研究背景

Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]).[supplied by OMIM, Jul 2010],

 

研究领域

Pathology


  • 027-87002838

  • order@enkilife.cn

  • 微信客服
  • 企业微信
  • 在线留言
    关闭