IRF-4/MUM1 Mouse Monoclonal Antibody-EnkiLife

IRF-4/MUM1 Mouse Monoclonal Antibody

Cat: AMM22135

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规格：50μL 价格：￥1200
规格：100μL 价格：￥2150
应用（Application）：IHC,ELISA
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：IRF4 MUM1
分类: 病理IHC抗体标签: Mouse, Pathology, Unconjugated, IHC, ELISA, Human

说明书复制

产品概述

产品名称（Product Name）	IRF-4/MUM1 Mouse Monoclonal Antibody
描述（Description）	病理IHC抗体
宿主（Host）	Mouse
应用（Application）	IHC,ELISA
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	IgG1,Kappa
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
纯化方式（Purification）	The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

免疫原

基因名（Gene Name）	IRF4 MUM1
别名（Alternative Names）	Interferon regulatory factor 4;IRF-4;Lymphocyte-specific interferon regulatory factor;LSIRF;Multiple myeloma oncogene 1;NF-EM5;
基因ID（Gene ID）	Human:3662
蛋白ID（SwissProt ID）	Human:Q15306

产品应用

稀释比（Dilution Ratio）	IHC 1:200-400;ELISA 1:500-5000
蛋白分子量（Molecular Weight）	Calculated MW:52kDa,Observed MW:52kDa

研究背景

The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010],

研究领域

Pathology