Cip4 Rabbit Monoclonal Antibody

Cip4 Rabbit Monoclonal Antibody

规格:20μL 价格:¥680
规格:50μL 价格:¥1350
规格:100μL 价格:¥2250
应用(Application):WB

种属(Reactivity):Human
偶联物(Conjugate):Unconjugated
基因名(Gene Name):Cip4
SKU: AMRe87308 Category: 兔单克隆抗体 Tags: , , ,

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产品概述

产品名称(Product Name)

Cip4 Rabbit Monoclonal Antibody

描述(Description)

Recombinant rabbit monoclonal antibody

宿主(Host)

Rabbit

应用(Application)

WB

种属反应性(Reactivity)

Human

 

产品性能

偶联物(Conjugation)

Unconjugated

修饰(Modification)

Unmodified

同种型(Isotype)

IgG

克隆(Clonality)

Monoclonal

形式(Form)

Liquid

存放说明(Storage)

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

储存溶液(Buffer)

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% protective protein. Stable for 12 months from date of receipt.

纯化方式(Purification)

Affinity Purification

 

免疫原

基因名(Gene Name)

Cip4

别名(Alternative Names)

STP; CIP4; HSTP; STOT; TRIP-10

基因ID(Gene ID)

9322

蛋白ID(SwissProt ID)

Q15642

 

产品应用

稀释比(Dilution Ratio)

WB 1:1000-1:5000

蛋白分子量(Molecular Weight)

Calculated MW:68 kDa; Observed MW:80 kDa

 

研究背景

Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.

 

研究领域


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