Aprataxin Rabbit Monoclonal Antibody-EnkiLife

Aprataxin Rabbit Monoclonal Antibody

规格：50μL 价格：￥1350
规格：100μL 价格：￥2250
应用（Application）：WB,ICC
种属（Reactivity）：Human
偶联物（Conjugate）：Unconjugated
基因名（Gene Name）：Aprataxin SKU: AMRe85300 Category: 兔单克隆抗体 Tags: Rabbit, Unconjugated, WB, ICC, Human

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产品概述

产品名称（Product Name）	Aprataxin Rabbit Monoclonal Antibody
描述（Description）	Recombinant rabbit monoclonal antibody
宿主（Host）	Rabbit
应用（Application）	WB,ICC
种属反应性（Reactivity）	Human

产品性能

偶联物（Conjugation）	Unconjugated
修饰（Modification）	Unmodified
同种型（Isotype）	IgG
克隆（Clonality）	Monoclonal
形式（Form）	Liquid
存放说明（Storage）	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
储存溶液（Buffer）	Purified antibody in TBS with 0.05% sodium azide,0.05%protective protein and 50% glycerol.
纯化方式（Purification）	Affinity Purification

免疫原

基因名（Gene Name）	Aprataxin
别名（Alternative Names）	AOA; AOA1; AXA1; EAOH; EOAHA; FHA-HIT
基因ID（Gene ID）	54840
蛋白ID（SwissProt ID）	Q7Z2E3

产品应用

稀释比（Dilution Ratio）	WB 1:500-1:1000,ICC 1:50-1:200
蛋白分子量（Molecular Weight）	Calculated MW: 41 kDa; Observed MW: 41 kDa

研究背景

DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair (PubMed:15380105, PubMed:15044383, PubMed:16964241, PubMed:17276982, PubMed:24362567). Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species (PubMed:16964241, PubMed:24362567). Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined (PubMed:16964241, PubMed:17276982, PubMed:24362567). Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH2) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity (PubMed:16547001). Likewise, catalyzes the release of 3'-linked guanosine (DNAppG) and inosine (DNAppI) from DNA, but has higher specific activity with 5'-linked adenosine (AppDNA) .

研究领域